In rat studies, Semax bound in the basal forebrain and raised levels of BDNF — a protein that helps brain cells grow and repair — above untreated controls.
Rat basal forebrain; directional finding, magnitudes illustrative.
Search peptides — top sellers first
Search peptides — top sellers first
Search peptides — top sellers first
Boosts BDNF and protects the brain after ischemia
Made in USA — Synthesized in our cGMP-compliant US facility
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Frequently bought together
Researchers usually add these to complete the protocol.

BAC Water · 3ml
Essential · extras

GHK-CU · 50mg
recovery

Melanotan 2 · 10mg
Tanning
Semax · 10mg
Certificate of analysis
We don't publish a brand-wide spec sheet and call it a “COA.” The certificate you receive references the actual lot number stamped on your vial — with the raw chromatograms attached.
Freedom Diagnostics
Independent analytical lab
Certificate of Analysis
RESULT · PASS
Analytical results
HPLC Chromatogram
Main peak 99.11% · other 0.89%
Alex Johnson
Principal Chemist
Scanned 17×
Know your compound
Semax is a short synthetic peptide based on a fragment of the hormone ACTH. It was developed in Russia and is used there in stroke and cognition research.
What grabs researchers is its effect on BDNF — brain-derived neurotrophic factor, a protein that helps brain cells grow, repair, and form new connections. In rat studies Semax raised BDNF in the brain and switched on genes tied to neural repair after a stroke-like injury.

For research use only — not for human or veterinary use.
The research
The published findings behind this compound — the headline numbers, in plain terms, each cited to source. Preclinical results are directional (animal / in-vitro) and shown for context, not as therapeutic claims.
In rat studies, Semax bound in the basal forebrain and raised levels of BDNF — a protein that helps brain cells grow and repair — above untreated controls.
Rat basal forebrain; directional finding, magnitudes illustrative.
After a stroke-like injury in rats, Semax switched on genes for neurotrophins and their receptors — the growth-factor machinery tied to neural repair.
Rat cerebral ischemia; transcription upregulated vs control.
In rodents, Semax activated the brain's dopamine and serotonin systems — the signaling pathways behind mood, motivation and focus.
Rodent brain; directional finding, magnitudes illustrative.
Semax has been studied in people at different stages of ischemic stroke, tracing its path from lab findings toward clinical evaluation.
2006
Raised BDNF in rat brain
2010
Repair genes activated
2018
Studied in stroke patients
Research settings only; not an efficacy claim.

Mechanism
A nootropic research peptide studied for boosting the brain's growth and repair signals.
Studied for raising BDNF, a protein that helps brain cells grow and form new connections.
Investigated for switching on repair genes after a stroke-like injury in rat models.
Researched for effects on the dopamine and serotonin systems.
For research use only. Mechanisms described reflect published research literature.
The process
Synthesized
Produced under controlled manufacturing with documented, repeatable processes.
HPLC purity
An independent lab reports the exact purity of every lot — a number, never a 'passes'.
Mass-spec identity
Molecular weight confirms the exact sequence is what the label says.
COA published
The certificate is posted to the open library, by lot, before the vial ships.
Best sellers
FAQ
Common questions about Semax
The COA guarantee
Have any lot independently re-tested. If the results don't match the published certificate, we refund the order in full — no returns, no questions.
Order with coverThird-party tested
An independent, accredited lab — no commercial interest in the result.
A COA on every lot
A lot-specific certificate ships with each vial, archived by batch.
Test it yourself → refund
Re-test any batch at any lab. A mismatch is a full refund.