In a placebo-controlled study of premenopausal women with sexual arousal disorder, bremelanotide (PT-141) increased subjective sexual response compared with placebo.
Directional finding — relative heights, not exact magnitudes.
Search peptides — top sellers first
Search peptides — top sellers first
Search peptides — top sellers first
The brain-based sexual pathway PDE5 drugs never touch
Made in USA — Synthesized in our cGMP-compliant US facility
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Frequently bought together
Researchers usually add these to complete the protocol.

BAC Water · 3ml
Essential · extras

GHK-CU · 50mg
recovery

Melanotan 2 · 10mg
Tanning
PT-141 · 10mg
Certificate of analysis
We don't publish a brand-wide spec sheet and call it a “COA.” The certificate you receive references the actual lot number stamped on your vial — with the raw chromatograms attached.
Freedom Diagnostics
Independent analytical lab
Certificate of Analysis
RESULT · PASS
Analytical results
HPLC Chromatogram
Main peak 99.91% · other 0.09%
Alex Johnson
Principal Chemist
Scanned 9×
Know your compound
PT-141 (bremelanotide) is a lab peptide that works in the brain instead of the blood vessels. It switches on melanocortin receptors — signaling switches in the central nervous system tied to sexual arousal.
Unlike sildenafil and other PDE5 drugs that rely on blood flow, PT-141 triggers arousal through brain signaling — a completely different route that still works when the vascular pathway doesn't. That mechanistic split is why it drew a decade of clinical and preclinical attention across both male and female sexual dysfunction research.

For research use only — not for human or veterinary use.
The research
The published findings behind this compound — the headline numbers, in plain terms, each cited to source. Preclinical results are directional (animal / in-vitro) and shown for context, not as therapeutic claims.
In a placebo-controlled study of premenopausal women with sexual arousal disorder, bremelanotide (PT-141) increased subjective sexual response compared with placebo.
Directional finding — relative heights, not exact magnitudes.
In men with mild-to-moderate erectile dysfunction, intranasal PT-141 produced measurable pharmacodynamic effects on erectile response versus placebo.
Directional pharmacodynamic finding — relative heights.
Mechanistic research suggests PT-141 acts on melanocortin receptors in the brain to drive arousal — a central pathway separate from the blood-flow (PDE5) route used by drugs like sildenafil.
Acts independent of nitric oxide / PDE5 vascular signaling.
In female rats, a melanocortin receptor agonist selectively increased sexual solicitation behavior compared with controls.
Directional preclinical finding — relative heights.

Mechanism
A melanocortin research peptide studied for driving arousal through the brain, not blood flow.
Studied for triggering arousal through MC4R brain signalling rather than the vascular route.
Investigated for working through a pathway that still responds when blood-flow drugs do not.
Researched across both male and female sexual-response models.
For research use only. Mechanisms described reflect published research literature.
The process
Synthesized
Produced under controlled manufacturing with documented, repeatable processes.
HPLC purity
An independent lab reports the exact purity of every lot — a number, never a 'passes'.
Mass-spec identity
Molecular weight confirms the exact sequence is what the label says.
COA published
The certificate is posted to the open library, by lot, before the vial ships.
Best sellers
FAQ
Common questions about PT-141
The COA guarantee
Have any lot independently re-tested. If the results don't match the published certificate, we refund the order in full — no returns, no questions.
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An independent, accredited lab — no commercial interest in the result.
A COA on every lot
A lot-specific certificate ships with each vial, archived by batch.
Test it yourself → refund
Re-test any batch at any lab. A mismatch is a full refund.