Search peptides — top sellers first
Search peptides — top sellers first
Search peptides — top sellers first
One peptide, two proven melanocortin pathways in research
Made in USA — Synthesized in our cGMP-compliant US facility
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Frequently bought together
Researchers usually add these to complete the protocol.
BAC Water · 3ml
Essential · extras
GHK-CU · 50mg
recovery
NAD+ · 100mg
Longevity
Melanotan 2 · 10mg
Certificate of analysis
We don't publish a brand-wide spec sheet and call it a “COA.” The certificate you receive references the actual lot number stamped on your vial — with the raw chromatograms attached.
Freedom Diagnostics
Independent analytical lab
Certificate of Analysis
RESULT · PASS
Analytical results
HPLC Chromatogram
Main peak 99.81% · other 0.19%
Alex Johnson
Principal Chemist
Scanned 12×
Know your compound
Melanotan 2 is a lab-made copy of alpha-MSH, a natural signaling hormone. It fits into several melanocortin receptors — the switches that control skin pigment and certain brain signals.
What makes it stand out is its reach: a single molecule that flips more than one receptor at once. Researchers use it to study MC1R (which drives melanin, the pigment that darkens skin) and MC4R (a brain receptor tied to appetite and libido), making it a versatile tool across dermatology and neuroscience.
For research use only — not for human or veterinary use.
The research
The published findings behind this compound — the headline numbers, in plain terms, each cited to source. Preclinical results are directional (animal / in-vitro) and shown for context, not as therapeutic claims.
In receptor pharmacology studies, Melanotan 2 engaged more than one melanocortin pathway — activity was documented at both MC1R, tied to skin pigment, and MC4R, tied to brain circuits for appetite.
Two melanocortin receptor subtypes engaged by one molecule
In mice, the melanocortin-driven appetite-suppression response was blunted when the Sim1 gene was disrupted — evidence that this feeding pathway depends on intact melanocortin signaling.
Feeding-suppression response and PVN neuron activation reduced when signaling disrupted
In knockout mice, disrupting the Gpr45 gene lowered hypothalamic POMC expression — the melanocortin precursor — and the animals became obese, linking this signaling arm to body-weight control.
Lower POMC expression tracked with an obese phenotype
In mice lacking CAPS2, POMC built up in the pituitary and feeding behavior shifted — further tying the melanocortin system that Melanotan 2 targets to how animals regulate food intake.
POMC accumulation in the pituitary accompanied changed food-intake behavior
Mechanism
A melanocortin research peptide studied for flipping more than one receptor with a single molecule.
Studied for activating MC1R, the receptor that drives melanin and skin pigment.
Investigated for MC4R, a brain receptor tied to appetite and sexual behaviour.
Researched as a versatile tool across dermatology and neuroscience for its multi-receptor reach.
For research use only. Mechanisms described reflect published research literature.
The process
Synthesized
Produced under controlled manufacturing with documented, repeatable processes.
HPLC purity
An independent lab reports the exact purity of every lot — a number, never a 'passes'.
Mass-spec identity
Molecular weight confirms the exact sequence is what the label says.
COA published
The certificate is posted to the open library, by lot, before the vial ships.
Best sellers
FAQ
Common questions about Melanotan 2
The COA guarantee
Have any lot independently re-tested. If the results don't match the published certificate, we refund the order in full — no returns, no questions.
Order with coverThird-party tested
An independent, accredited lab — no commercial interest in the result.
A COA on every lot
A lot-specific certificate ships with each vial, archived by batch.
Test it yourself → refund
Re-test any batch at any lab. A mismatch is a full refund.
