In a colitis mouse model, KPV loaded into colon-targeted nanoparticles reduced inflammation in the gut lining compared with untreated animals.
DSS-induced colitis mouse model; magnitudes illustrate direction, not exact values.
Search peptides — top sellers first
Search peptides — top sellers first
Search peptides — top sellers first
Calms gut and skin inflammation — no immune shutdown
Made in USA — Synthesized in our cGMP-compliant US facility
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Frequently bought together
Researchers usually add these to complete the protocol.

BAC Water · 3ml
Essential · extras

GHK-CU · 50mg
recovery

Melanotan 2 · 10mg
Tanning
KPV · 10mg
Certificate of analysis
We don't publish a brand-wide spec sheet and call it a “COA.” The certificate you receive references the actual lot number stamped on your vial — with the raw chromatograms attached.
Freedom Diagnostics
Independent analytical lab
Certificate of Analysis
RESULT · PASS
Analytical results
HPLC Chromatogram
Main peak 99.75% · other 0.25%
Alex Johnson
Principal Chemist
Scanned 8×
Know your compound
KPV is a tiny three-part peptide (lysine-proline-valine) snipped from the tail of alpha-MSH, a natural anti-inflammatory hormone. Researchers study it for how it quiets inflammation in gut and skin tissue.
What caught attention: in colitis-model studies, KPV eased inflammation without switching off the immune system — a different route than steroids or standard anti-inflammatory drugs. It also slips into cells through a nutrient transporter called PepT1, which packs it right into inflamed gut lining where it's needed.

For research use only — not for human or veterinary use.
The research
The published findings behind this compound — the headline numbers, in plain terms, each cited to source. Preclinical results are directional (animal / in-vitro) and shown for context, not as therapeutic claims.
In a colitis mouse model, KPV loaded into colon-targeted nanoparticles reduced inflammation in the gut lining compared with untreated animals.
DSS-induced colitis mouse model; magnitudes illustrate direction, not exact values.
KPV was shown to enter intestinal lining cells through PepT1 — a nutrient transporter — which delivered it directly into inflamed tissue and dampened the local inflammatory response.
Intestinal epithelial cells and mouse colitis model; relative heights show direction.
In immune-cell research, alpha-MSH-derived peptides including KPV were associated with turning down pro-inflammatory cytokine signalling.
Review of immune-cell studies; directional finding, not a measured percentage.

Mechanism
An α-MSH-derived research peptide studied for calming inflammation with a targeted route into cells.
Studied in colitis models for easing inflammation without switching off the immune system.
Investigated for entering cells through the PepT1 nutrient transporter, concentrating in inflamed gut lining.
Researched for dampening the inflammatory signals that drive intestinal disease models.
For research use only. Mechanisms described reflect published research literature.
The process
Synthesized
Produced under controlled manufacturing with documented, repeatable processes.
HPLC purity
An independent lab reports the exact purity of every lot — a number, never a 'passes'.
Mass-spec identity
Molecular weight confirms the exact sequence is what the label says.
COA published
The certificate is posted to the open library, by lot, before the vial ships.
Best sellers
FAQ
Common questions about KPV
The COA guarantee
Have any lot independently re-tested. If the results don't match the published certificate, we refund the order in full — no returns, no questions.
Order with coverThird-party tested
An independent, accredited lab — no commercial interest in the result.
A COA on every lot
A lot-specific certificate ships with each vial, archived by batch.
Test it yourself → refund
Re-test any batch at any lab. A mismatch is a full refund.